Ji lab, May 2025
What’s new:
January 2025: Find out how the microscopes in the Ji lab have been used by our collaborators for characterizing complex materials, testing voltage sensors, and studying synaptic plasticity.
January 2025: Congratulations to Guanghan Meng, the first PhD student from the Ji lab, for starting her own lab at School of Optometry, UC Berkeley!
December 2024: Congratulations to Jian Zhong and Daisong Pan for graduating with PhDs in Physics from the Ji lab!
November 2024: Read our preprint on a machine-learning-based method for measuring and correcting aberrations in two-photon fluorescence microscopy. This method works with commercial microscope and improve image quality in the mouse brain in vivo.
August 2024: Read the review article on how multiphoton fluorescence microscopy has been utilized for in vivo investigations in neuroscience, cancer biology, and immunology, in the special issue of Cell on the wide-reaching power of technology.
July 2024: We have expanded the application of multiplexed aberration measurement method from two-photon and three-photon fluorescence microscopy to confocal fluorescence and third-harmonic generation microscopy, working collaboratively with many colleagues who provided samples ranging from plants, zebrafish larvae, and mice.
June 2024: Read our new paper using machine learning for aberration measurement for widefield fluorescence microscopy, a project led by Iksung and Qinrong, with Stella Yu as our collaborator!
June 2024: Read our new paper on high-throughput volumetric mapping of synaptic transmission. By using Bessel-droplet foci for volumetric glutamate imaging, we were able to map excitatory inputs at >1,000 synapses per volume and >500 dendritic spines per neuron in vivo, using a standard Ti:Sapphire laser and a commercial microscope. Congratulations and thanks to Wei and Xinxin Ge (with the Scanziani lab) and the rest of the team!
April 2024: Read our preprint on using third-harmonic generation microscopy for label-free imaging of plant roots and microbes, a collaborative work with plant biologists at the DOE Joint Genome Institute and LBNL.
August 2023: Read our new paper on how the edge of visual stimulus can induce orientation columns in the mouse superior colliculus. Congratulations and thanks to Yajie, Rongwen, and Katharine, for years of careful and hard work!
May 2023: Read our two collaborative studies with the Gong lab at the School of Optometry and with the Chen lab at Nutritional Science & Toxicology, where microscopes in the Ji lab were used to image the lens cells and neurons in aging dentate gyrus in vivo.
April 2023: Congratulations, Qinrong, on having two papers published in the same month! Read our invited review on adaptive optics for optical microscopy and learn about our adaptive optical two-photon fluorescence microscopy designed to image the mouse retinal at high resolution in vivo.
December 2022: Kevin and Yuhan submitted their Ph.D. theses. Congratulations, Dr. Fan and Dr. Yang!
August 2022: Hyeonggeon (Ed) Kim has joined the Ji lab as a graduate student from the AS&T program. Welcome, Ed!
August 2022: Cristina is moving to New Haven to start her assistant professor position in Yale Biomedical Engineering. Congratulations, Cristina!
July 2022: Dr. Iksung Kang has joined the Ji lab as a postdoctoral fellow. Welcome!
June 2022: Read our PNAS paper on ultrafast two-photon imaging of blood flow in the living mouse brain and the accompanying commentary on how we achieved a “FACED lift” for blood flow imaging. Congratulations, Guanghan, Jian, and Qinrong, and our collaborators from the Tsia lab!
May 2022: Congratulations, Emma, for winning the I.L. Chaikoff Memorial Award received for “outstanding achievement and excellence in research in the Cell & Developmental Biology and Neurobiology emphases” with her honor’s thesis in our lab!
November 2021: Read our paper on applying focal plane adaptive optics to Bessel foci, which enabled volumetric recording of synaptic calcium and glutamate activity at high resolution in Nature Communications. Well done, Wei, and collaborators in both Ji and Isacoff labs!
October 2021: Congratulations, Cristina, for being selected as an ISFS (Intersections Science Fellows Symposium) Fellow!
October 2021: Congratulations to Cristina, Anderson, and collaborators on the publication of the adaptive module paper at Nature Methods. Well done!
April 2021: Guanghan submitted her PhD thesis. Congratulations, Dr. Meng (and the first PhD graduate from the Ji lab)!
March 2021: Guanghan won the Best Presentation Award of the “High-Speed Biomedical Imaging and Spectroscopy” Conference at SPIE Photonics West. Congratulations, Guanghan!
Earlier news…
